Picrosirius Red Staining Kit
Product Sizes
50mL
£169.00
RA20129-50ML
About this Product
- SKU:
- RA20129
- Extra Details:
- Collagen fibers are the most widely distributed and abundant fibers in connective tissue; found extensively in various organs; especially in the skin; sclera; and tendons. Type I collagen is mainly found in bone; skin; and tendon fibers. Type II collagen is primarily located in cartilage. Type III collagen is mainly present in embryonic tissues and adult blood vessels and gastrointestinal tract. Type IV collagen is primarily found in the basement membrane. Both Picrosirius Red and its counterstain are strongly acidic dyes that bind firmly to basic groups in collagen molecules. Under polarized light microscopy; collagen fibers exhibit positive uniaxial birefringence. When combined with Picrosirius Red; this birefringence is enhanced; improving resolution and allowing differentiation between collagen types. EnkiLife Picrosirius Red Staining Kit consists of Hematoxylin Staining Solution and Picrosirius Red Staining Solution. It is mainly used to study abnormal collagen fibers or fibrosis in various pathological tissues. Under a standard light microscope; collagen fibers in tissues such as heart and blood vessels are stained red. Under polarized light microscopy; it aids in the classification and grading of fibrotic lesions. Although immunohistochemistry can also be used to detect Type I and Type III collagen fibers; the antibodies are expensive and the procedure is time-consuming. In contrast; Picrosirius Red staining is cost-effective and simple to perform.
- Research Area:
- Pathology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- store at 2-8[o]C for 12 months; keep away from light
- Type:
- Assay Kits: Staining & Imaging
