Myelin Staining Kit;Luxol Fast Blue (LFB) Method
Product Sizes
50mL
£162.00
RA20125-50ML
About this Product
- SKU:
- RA20125
- Extra Details:
- The myelin sheath is a membrane that wraps around the axons of nerve cells. It is composed of myelin-forming cells and their cell membranes; forming a multilayered lipid bilayer structure through spiral wrapping of the neural membrane cell’s plasma membrane along the axonal axis. The myelin sheath contains nodes of Ranvier; which allow for saltatory conduction of nerve impulses. Myelin staining is of certain significance in pathological diagnosis. Pathological changes in myelin can be divided into early; middle; and late stages. In the early stage; myelin stains deeply; in the middle stage; degenerated myelin forms lipid droplets; which can be demonstrated with lipid stains; in the late stage; myelin is completely degraded and removed by phagocytes; resulting in loss of positive staining. Many diseases can cause changes in myelin. Luxol Fast Blue myelin staining can reveal whether the myelin is intact; degenerated; or necrotic under pathological conditions; as well as the extent of repair. It is valuable for pathological diagnosis and research of neural tissue. For example; when nerve fibers are damaged; the myelin may swell; become tortuous and spherical; break; or completely disappear.
- Research Area:
- Pathology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- store at RT for 12 months
- Type:
- Assay Kits: Staining & Imaging
