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Alizarin Red S Staining Kit;2%;pH 4.2

Product Sizes
100mL
£136.00
RA20117-100ML
About this Product
SKU:
RA20117
Extra Details:
Calcium is abundant in the human body; constituting the skeleton that supports the body and playing essential roles in secretion; transport; muscle contraction; and nerve conduction. Calcium exists in two forms: ionized calcium in the circulation (so-called blood calcium) and bound calcium that is deposited in tissues in combination with proteins; carbonate; or phosphate. Except for bone and teeth; calcium is normally distributed throughout all tissues and cells and usually does not appear in solid form; however; under certain conditions calcium precipitates and deposits in tissues as pathological calcification; mainly calcium phosphate and; to a lesser extent; calcium carbonate. Calcium salts are usually monorefringent; but calcium oxalate is birefringent. With H&E staining calcium appears generally bluish-purple. Many dyes can chelate calcium; including Alizarin Red S; purpurin; and nuclear fast red. Alizarin Red S; an anthraquinone derivative and the sodium salt of alizarin sulfonate; chelates calcium in calcium carbonate or calcium phosphate to form an orange-red complex. Alizarin Red S often yields more reliable results for small amounts of deposits and is frequently combined with Fast Green or Mayer’s hematoxylin to produce an orange-red precipitate; making it suitable for staining tissues containing scant calcium salts.
Research Area:
Pathology
Shipping Conditions:
Ambient
Storage Conditions:
store at RT for 12 months
Type:
Assay Kits: Staining & Imaging