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Antibodies

PPIG rabbit pAb

Product Sizes
50UL
£ POA
ES9975-50UL
100UL
£ POA
ES9975-100UL
About this Product
SKU:
ES9975
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).;domain:The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.;enzyme regulation:Cyclosporin A (CsA)-sensitive.;function:PPIases accelerate the folding of proteins.;function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.;function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding; transport; and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Belongs to the cyclophilin-type PPIase family.;similarity:Contains 1 PPIase cyclophilin-type domain.;subcellular location:Colocalizes with RNA splicing factors at nuclear speckles.;subunit:Interacts with CLK1; PNN and with the phosphorylated C-terminal domain of RNA polymerase II.;tissue specificity:Ubiquitous.;
Immunogen:
Synthesized peptide derived from human protein . at AA range: 290-370
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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