OAZ3 rabbit pAb
Product Sizes
50UL
£ POA
ES9964-50UL
100UL
£ POA
ES9964-100UL
About this Product
- SKU:
- ES9964
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family; which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting; which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC); the key enzyme in polyamine biosynthesis; thus; completing the auto-regulatory circuit. This gene encodes antizyme 3; the third member of the antizyme family. Like antizymes 1 and 2; antizyme 3 inhibits ODC activity and polyamine uptake; however; it does not stimulate ODC degradation. Also; while antizymes 1 and 2 have broad tissue distribution; expression of antizyme 3 is restricted to haploid germ cells in testis; suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies showed that ho
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 90-170
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
