OAZ2 rabbit pAb
Product Sizes
50UL
£ POA
ES9963-50UL
100UL
£ POA
ES9963-100UL
About this Product
- SKU:
- ES9963
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family; which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting; which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC); the key enzyme in polyamine biosynthesis; thus; completing the auto-regulatory circuit. This gene encodes antizyme 2; the second member of the antizyme family. Like antizyme 1; antizyme 2 has broad tissue distribution; inhibits ODC activity and polyamine uptake; and stimulates ODC degradation in vivo; however; it fails to promote ODC degradation in vitro. Antizyme 2 is expressed at lower levels than antizyme 1; but is evolutionary more conserved; suggesting it likely has an important biological role. Studies also show different sub
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 90-170
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
