NR0B2 rabbit pAb
Product Sizes
50UL
£ POA
ES9945-50UL
100UL
£ POA
ES9945-100UL
About this Product
- SKU:
- ES9945
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family; a group of transcription factors regulated by small hydrophobic hormones; a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors; inhibiting their ligand-dependent transcriptional activation. In addition; interaction with estrogen receptors has been demonstrated; leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 30-110
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
