NIPBL rabbit pAb
Product Sizes
50UL
£ POA
ES9928-50UL
100UL
£ POA
ES9928-100UL
About this Product
- SKU:
- ES9928
- Application:
- Immunohistochemistry, Immunofluorescence
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion; chromosome condensation; and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins; cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome; a disorder characterized by dysmorphic facial features; growth delay; limb reduction defects; and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 560-640
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
