NU3M rabbit pAb
Product Sizes
50UL
£ POA
ES9883-50UL
100UL
£ POA
ES9883-100UL
About this Product
- SKU:
- ES9883
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.;disease:Defects in MT-ND3 are a cause of complex I mitochondrial respiratory chain deficiency [MIM:252010]. Complex I (NADH-ubiquinone oxidoreductase); the largest complex of the mitochondrial respiratory chain; contains more than 40 subunits. It is embedded in the inner mitochondrial membrane and is partly protruding in the matrix. Complex I deficiency is the most common cause of mitochondrial disorders. It represents largely one-third of all cases of respiratory chain deficiency and is responsible for a variety of clinical symptoms; ranging from neurological disorders to cardiomyopathy; liver failure; and myopathy.;disease:Defects in MT-ND3 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.;function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.;similarity:Belongs to the complex I subunit 3 family.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 20-100
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
