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Antibodies

MED31 rabbit pAb

Product Sizes
50UL
£ POA
ES9792-50UL
100UL
£ POA
ES9792-100UL
About this Product
SKU:
ES9792
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
function:Component of the Mediator complex; a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.;similarity:Belongs to the Mediator complex subunit 31 family.;subunit:Component of the Mediator complex; which is composed of MED1; MED4; MED6; MED7; MED8; MED9; MED10; MED11; MED12; MED13; MED13L; MED14; MED15; MED16; MED17; MED18; MED19; MED20; MED21; MED22; MED23; MED24; MED25; MED26; MED27; MED29; MED30; MED31; CCNC; CDK8 and CDC2L6/CDK11. The MED12; MED13; CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC; CRSP; DRIP; PC2; SMCC and TRAP.;
Immunogen:
Synthesized peptide derived from human protein . at AA range: 1-80
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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