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Antibodies

DQB2 rabbit pAb

Product Sizes
50UL
£ POA
ES9713-50UL
100UL
£ POA
ES9713-100UL
About this Product
SKU:
ES9713
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
major histocompatibility complex; class II; DQ beta 2(HLA-DQB2) Homo sapiens HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB); both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity; and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene; HLA-DQB2; is not routinely typed; as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF; HLA-DQ
Immunogen:
Synthesized peptide derived from part region of human protein
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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