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Antibodies

MMP25 rabbit pAb

Product Sizes
50UL
£ POA
ES9209-50UL
100UL
£ POA
ES9209-100UL
About this Product
SKU:
ES9209
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However; the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation; the encoded protein is thought to inactivate alpha-1 proteinase inhibitor; a major tissue protectant against proteolytic enzymes released by activated neutrophils; facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in
Immunogen:
Synthesized peptide derived from human protein . at AA range: 10-90
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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