DMP1 rabbit pAb
Product Sizes
50UL
£ POA
ES9058-50UL
100UL
£ POA
ES9058-100UL
About this Product
- SKU:
- ES9058
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein; which is critical for proper mineralization of bone and dentin; is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains; multiple phosphorylation sites; a functional arg-gly-asp cell attachment sequence; and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix; where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia; a disease that manifests as rickets and osteomalacia. The gene structure is conser
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 430-510
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
