ASAP2 rabbit pAb
Product Sizes
50UL
£ POA
ES8991-50UL
100UL
£ POA
ES8991-100UL
About this Product
- SKU:
- ES8991
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif; followed by a pleckstrin homology (PH) domain; an Arf-GAP domain; an ankyrin homology region; a proline-rich region; and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane; where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro; and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 640-720
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
