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Antibodies

LRP6 rabbit pAb

Product Sizes
50UL
£ POA
ES8988-50UL
100UL
£ POA
ES8988-100UL
About this Product
SKU:
ES8988
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or; with Frizzled; a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation; proliferation; and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq; Dec 2009];
Immunogen:
Synthesized peptide derived from human protein . at AA range: 1420-1500
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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