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Antibodies

CCR5 rabbit pAb

Product Sizes
50UL
£ POA
ES8888-50UL
100UL
£ POA
ES8888-100UL
About this Product
SKU:
ES8888
Additional Names:
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the beta chemokine receptor family; which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages; and is known to be an important co-receptor for macrophage-tropic virus; including HIV; to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2); macrophage inflammatory protein 1 alpha (MIP-1 alpha); macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line; suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok
Immunogen:
Synthesized peptide derived from human CCR5 Polyclonal
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Type:
Antibodies: Polyclonal Antibody
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