C1RL rabbit pAb
Product Sizes
50UL
£ POA
ES8873-50UL
100UL
£ POA
ES8873-100UL
About this Product
- SKU:
- ES8873
- Additional Names:
- Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- caution:Does not associate with the C1 complex. According to PubMed:15385675 doesn't cleave the proform of complement C1s.;function:Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.;induction:Up-regulated in monocytes and dendritic cells (DC) undergoing maturation or activation.;similarity:Belongs to the peptidase S1 family.;similarity:Contains 1 CUB domain.;similarity:Contains 1 peptidase S1 domain.;tissue specificity:Highly expressed in placenta; liver; kidney; pancreas; moderately in lung; spleen; prostate; ovary; colon; and PBL; and weakly in heart; skeletal muscle; thymus; testis; and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells; but not in LoVo and HT-29 (colon adenocarcinoma); SMMC7721 (hepatocellular carcinoma); CaoV-3 (ovary adenocarcinoma); HeLa (cervix epithelioid carcinoma); MCF-7 (breast adenocarcinoma); U251 (glioma) or A549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines; including K-562 (chronic myelogenous leukemia); THP-1 (myelomonocytic leukemia); HL-60 and NB4 (promyelocytic leukemia); and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).;
- Immunogen:
- Synthesized peptide derived from human C1RL. at AA range: 371-420
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
