IL-15 rabbit pAb
Product Sizes
50UL
£ POA
ES8801-50UL
100UL
£ POA
ES8801-100UL
About this Product
- SKU:
- ES8801
- Additional Names:
- Interleukin-15 (IL-15)
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits; and may compete for the same receptor; and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases; as well as the phosphorylation and activation of transcription activators STAT3; STAT5; and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L); possibly through the transcription activation activity of STAT6; and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq; Feb
- Immunogen:
- Synthetic peptide from human protein at AA range: 111-160
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
