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Antibodies

FAS-L rabbit pAb

Product Sizes
50UL
£ POA
ES8795-50UL
100UL
£ POA
ES8795-100UL
About this Product
SKU:
ES8795
Additional Names:
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand;APTL;CD95 ligand;CD95-L;Fas antigen ligand;Fas ligand;FasL;CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6; membrane form; Tumor necrosis factor ligand superfamily member 6; soluble form (Receptor-binding FasL ectodomain;Soluble Fas ligand;sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD;SPPL2A-processed FasL form;SPA)]
Application:
Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation; including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq; Nov 2014];
Immunogen:
Synthetic peptide from human protein at AA range: 121-170
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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