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Antibodies

Insulin rabbit pAb

Product Sizes
50UL
£ POA
ES8775-50UL
100UL
£ POA
ES8775-100UL
About this Product
SKU:
ES8775
Additional Names:
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Application:
Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
After removal of the precursor signal peptide; proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides; which are covalently linked via two disulfide bonds to form insulin; and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene; INS-IGF2; which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Jun 2010];
Immunogen:
Synthetic peptide from human protein at AA range: 30-70
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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