HLA-DQA1 rabbit pAb
Product Sizes
50UL
£ POA
ES8761-50UL
100UL
£ POA
ES8761-100UL
About this Product
- SKU:
- ES8761
- Additional Names:
- HLA class II histocompatibility antigen; DQ alpha 1 chain (DC-1 alpha chain;DC-alpha;HLA-DCA;MHC class II DQA1)
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB); both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes; dendritic cells; macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities; resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marro
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human HLA-DQA1. AA range:21-70
- Isotype:
- IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
