CD204 rabbit pAb
Product Sizes
50UL
£ POA
ES8700-50UL
100UL
£ POA
ES8700-100UL
About this Product
- SKU:
- ES8700
- Additional Names:
- Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II;Scavenger receptor class A member 1;CD antigen CD204)
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes the class A macrophage scavenger receptors; which include three different types (1; 2; 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis; Alzheimer's disease; and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum; making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human MSR1. AA range:241-290
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
