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Antibodies

SOCS-3 rabbit pAb

Product Sizes
50UL
£ POA
ES8666-50UL
100UL
£ POA
ES8666-100UL
About this Product
SKU:
ES8666
Additional Names:
Suppressor of cytokine signaling 3 (SOCS-3;Cytokine-inducible SH2 protein 3;CIS-3;STAT-induced STAT inhibitor 3;SSI-3)
Application:
Western Blot, Immunohistochemistry, Immunofluorescence
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the STAT-induced STAT inhibitor (SSI); also known as suppressor of cytokine signaling (SOCS); family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines; including IL6; IL10; and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase; and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis; and placental development. [provided by RefSeq; Jul 2008];
Immunogen:
Synthetic peptide from human protein at AA range: 20-70
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Type:
Antibodies: Polyclonal Antibody
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