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Antibodies

COL25A1 rabbit pAb

Product Sizes
50UL
£ POA
ES8542-50UL
100UL
£ POA
ES8542-100UL
About this Product
SKU:
ES8542
Additional Names:
COL25A1
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein; CLAC (collagenous Alzheimer amyloid plaque component); binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice; however; found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Dec 2011];
Immunogen:
Synthetic peptide from human protein at AA range: 101-150
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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