Collagen IV rabbit pAb
Product Sizes
50UL
£ POA
ES8486-50UL
100UL
£ POA
ES8486-100UL
About this Product
- SKU:
- ES8486
- Additional Names:
- collagen; type IV; alpha 1
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain; a triple-helix forming collagenous domain; and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans; proteoglycans; and laminins. In addition; proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten; which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly; cerebrovascular disease; and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Dec 2014];
- Immunogen:
- Synthesized peptide derived from Collagen IV . at AA range: 1428-1443
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
