Amyloid-β rabbit pAb
Product Sizes
50UL
£ POA
ES8472-50UL
100UL
£ POA
ES8472-100UL
About this Product
- SKU:
- ES8472
- Additional Names:
- amyloid beta (A4) precursor protein
- Application:
- Immunofluorescence, Western Blot, Immunohistochemistry, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation; while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition; two of the peptides are antimicrobial peptides; having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq; Aug 2014];
- Immunogen:
- Synthesized peptide derived from Amyloid-β at AA range: 221-270
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
