CD35 rabbit pAb
Product Sizes
50UL
£ POA
ES8467-50UL
100UL
£ POA
ES8467-100UL
About this Product
- SKU:
- ES8467
- Additional Names:
- complement component (3b/4b) receptor 1/2 (Knops blood group)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes; leukocytes; glomerular podocytes; and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas; mesangiocapillary glomerulonephritis; systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting; conferring protection against severe malaria. Alternate allele-specific splice variants
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human CR1/CR1L. AA range:300-350 & 740-790
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
