p300 (Acetyl Lys1558/Acetyl Lys1560) rabbit pAb
Product Sizes
50UL
£ POA
ES8433-50UL
100UL
£ POA
ES8433-100UL
About this Product
- SKU:
- ES8433
- Additional Names:
- EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- E1A binding protein p300(EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha); and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized acetyl-peptide derived from human p300 around the acetylation site of K1558.
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
