RNase III Drosha rabbit pAb
Product Sizes
50UL
£ POA
ES8417-50UL
100UL
£ POA
ES8417-100UL
About this Product
- SKU:
- ES8417
- Additional Names:
- DROSHA; RN3; RNASE3L; RNASEN; Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- drosha ribonuclease III(DROSHA) Homo sapiens This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex; which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus; yielding the precursor miRNA (pre-miRNA); which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene; canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq; Sep 2016];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RNase III Drosha. AA range:774-823
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
