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Antibodies

Arnt 2 rabbit pAb

Product Sizes
50UL
£ POA
ES8125-50UL
100UL
£ POA
ES8125-100UL
About this Product
SKU:
ES8125
Additional Names:
ARNT2; BHLHE1; KIAA0307; Aryl hydrocarbon receptor nuclear translocator 2; ARNT protein 2; Class E basic helix-loop-helix protein 1; bHLHe1
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
aryl hydrocarbon receptor nuclear translocator 2(ARNT2) Homo sapiens This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family; forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions; the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins; suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis; respectively. [provided by RefSeq; Dec 2013];
Immunogen:
The antiserum was produced against synthesized peptide derived from human ARNT2. AA range:21-70
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Type:
Antibodies: Polyclonal Antibody
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