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Antibodies

Rabaptin-5α rabbit pAb

Product Sizes
50UL
£ POA
ES7966-50UL
100UL
£ POA
ES7966-100UL
About this Product
SKU:
ES7966
Additional Names:
RABEP1; RAB5EP; RABPT5; RABPT5A; Rab GTPase-binding effector protein 1; Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17
Application:
Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
function:Rab effector protein acting as linker between gamma-adaptin; RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.;PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.;similarity:Belongs to the rabaptin family.;subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2; GGA1; GGA2; GGA3; AP1G1 and AP1G2.;
Immunogen:
The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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