ERI1 rabbit pAb
Product Sizes
50UL
£ POA
ES7939-50UL
100UL
£ POA
ES7939-100UL
About this Product
- SKU:
- ES7939
- Additional Names:
- ERI1; 3'EXO; THEX1; 3'-5' exoribonuclease 1; 3'-5' exonuclease ERI1; Eri-1 homolog; Histone mRNA 3'-end-specific exoribonuclease; Histone mRNA 3'-exonuclease 1; Protein 3'hExo; HEXO
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- cofactor:Binds 2 magnesium ions per subunit.;enzyme regulation:Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA; the presence of SLBP prevents the exonuclease activity.;function:RNA exonuclease that binds to the 3'-end of histone mRNAs and probably degrades them; suggesting that it plays an essential role in histone mRNA decay after replication. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro; suggesting a possible role as regulator of RNA interference (RNAi). Required for 5.8S rRNA 3'-end processing.;sequence caution:Translated as Leu.;similarity:Contains 1 exonuclease domain.;similarity:Contains 1 SAP domain.;subunit:Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. Requires the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Also binds to 5.8s ribosomal RNA.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ERI1. AA range:261-310
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
