PXR rabbit pAb
Product Sizes
50UL
£ POA
ES7893-50UL
100UL
£ POA
ES7893-100UL
About this Product
- SKU:
- ES7893
- Additional Names:
- NR1I2; PXR; Nuclear receptor subfamily 1 group I member 2; Orphan nuclear receptor PAR1; Orphan nuclear receptor PXR; Pregnane X receptor; Steroid and xenobiotic receptor; SXR
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene product belongs to the nuclear receptor superfamily; members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4; binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4; including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms; some of which use non-AUG (CUG) translation initiation codon; have been described for this gene. Additional transcript variants exist; however; they have not been fully characterized. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human NR1I2. AA range:91-140
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
