GALR2 rabbit pAb
Product Sizes
50UL
£ POA
ES7881-50UL
100UL
£ POA
ES7881-100UL
About this Product
- SKU:
- ES7881
- Additional Names:
- GALR2; GALNR2; Galanin receptor type 2; GAL2-R; GALR-2
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Galanin is an important neuromodulator present in the brain; gastrointestinal system; and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion; inhibits cardiac vagal slowing of heart rate; abolishes sinus arrhythmia; and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq); in contrast to GALR1; which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However; it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GALR2. AA range:201-250
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
