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Antibodies

Golgin 45 rabbit pAb

Product Sizes
50UL
£ POA
ES7816-50UL
100UL
£ POA
ES7816-100UL
About this Product
SKU:
ES7816
Additional Names:
BLZF1; JEM1; Golgin-45; Basic leucine zipper nuclear factor 1; JEM-1; p45 basic leucine-zipper nuclear factor
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
caution:Because of the presence of a potential basic motif and leucine-zipper domain; PubMed:9129147 and PubMed:11056056 have thought that BLZF1 is a potential transcription factor. They found it localized in the nucleus; except isoform 2; which was cytoplasmic. However; homology at several typical position for basic or hydrophobic residues is missing.;function:Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.;induction:Up-regulated by retinoids.;subunit:Interacts with GORASP2 and with the GTP-bound form of RAB2; but not with other Golgi Rab proteins. GORASP2 and BLZF1 form a RAB2 effector complex on medial Golgi.;tissue specificity:Ubiquitous. Also found in cell lines derived from several hematopoietic pathologies; such as T-cell leukemia; pro-B; pre-B; myeloma; and plasmacytoma cell lines; but not in Burkitt lymphoma cells.;
Immunogen:
The antiserum was produced against synthesized peptide derived from human BLZF1. AA range:10-59
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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