COL25A1 rabbit pAb
Product Sizes
50UL
£ POA
ES7762-50UL
100UL
£ POA
ES7762-100UL
About this Product
- SKU:
- ES7762
- Additional Names:
- COL25A1; Collagen alpha-1(XXV) chain; Alzheimer disease amyloid-associated protein; AMY; CLAC-P
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein; CLAC (collagenous Alzheimer amyloid plaque component); binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice; however; found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Dec 2011];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Collagen XXV alpha1. AA range:101-150
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
