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Antibodies

Reg IV rabbit pAb

Product Sizes
50UL
£ POA
ES7723-50UL
100UL
£ POA
ES7723-100UL
About this Product
SKU:
ES7723
Additional Names:
REG4; GISP; RELP; Regenerating islet-derived protein 4; REG-4; Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
function:May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.;induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum.;online information:Regenerating protein IV;similarity:Contains 1 C-type lectin domain.;tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum; jejunum; ileum; ileocecum; appendix; descending colon; pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.;
Immunogen:
Synthesized peptide derived from the Internal region of human Reg IV.
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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