Frizzled-6 rabbit pAb
Product Sizes
50UL
£ POA
ES7668-50UL
100UL
£ POA
ES7668-100UL
About this Product
- SKU:
- ES7668
- Additional Names:
- FZD6; Frizzled-6; Fz-6; hFz6
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- frizzled class receptor 6(FZD6) Homo sapiens This gene represents a member of the 'frizzled' gene family; which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide; a cysteine-rich domain in the N-terminal extracellular region; and seven transmembrane domains; but unlike other family members; this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade; thereby inhibiting the processes that trigger oncogenic transformation; cell proliferation; and inhibition of apoptosis. Alternative splicing results in multiple transcript variants; some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq; Aug 2011];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human FZD6. AA range:116-165
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
