COL18A1 rabbit pAb
Product Sizes
50UL
£ POA
ES7622-50UL
100UL
£ POA
ES7622-100UL
About this Product
- SKU:
- ES7622
- Additional Names:
- COL18A1; Collagen alpha-1(XVIII) chain
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins; extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin; a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities; so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Dec 2014];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Collagen alpha1 XVIII. AA range:1301-1350
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
