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Antibodies

CAD (phospho Thr456) rabbit pAb

Product Sizes
50UL
£ POA
ES7563-50UL
100UL
£ POA
ES7563-100UL
About this Product
SKU:
ES7563
Additional Names:
CAD; CAD protein
Application:
Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II); aspartate transcarbamoylase; and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade; which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq; Apr 2015];
Immunogen:
The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456. AA range:422-471
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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