CA VIII rabbit pAb
Product Sizes
50UL
£ POA
ES7546-50UL
100UL
£ POA
ES7546-100UL
About this Product
- SKU:
- ES7546
- Additional Names:
- CA8; CALS; Carbonic anhydrase-related protein; CARP; Carbonic anhydrase VIII; CA-VIII
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However; the gene product lacks carbonic anhydrase activity (i.e.; the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia; mental retardation; and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis; and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid
- Immunogen:
- Synthesized peptide derived from the Internal region of human CA VIII.
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
