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Antibodies

RANTES rabbit pAb

Product Sizes
50UL
£ POA
ES7129-50UL
100UL
£ POA
ES7129-100UL
About this Product
SKU:
ES7129
Additional Names:
CCL5; D17S136E; SCYA5; C-C motif chemokine 5; EoCP; Eosinophil chemotactic cytokine; SIS-delta; Small-inducible cytokine A5; T cell-specific protein P228; TCP228; T-cell-specific protein RANTES
Application:
Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine; a member of the CC subfamily; functions as a chemoattractant for blood monocytes; memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5); and it suppresses in vitro replication of the R5 strains of HIV-1; which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode
Immunogen:
The antiserum was produced against synthesized peptide derived from human RANTES. AA range:35-84
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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