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Antibodies

SH-PTP1 (phospho Tyr536) rabbit pAb

Product Sizes
50UL
£ POA
ES6932-50UL
100UL
£ POA
ES6932-100UL
About this Product
SKU:
ES6932
Additional Names:
PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains; which act as protein phospho-tyrosine binding domains; and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells; and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with; and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene; which encode distinct isoforms; have been reported. [provided by RefSeq; Jul
Immunogen:
The antiserum was produced against synthesized peptide derived from human SHP-1 around the phosphorylation site of Tyr536. AA range:502-551
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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