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Antibodies

Patched rabbit pAb

Product Sizes
50UL
£ POA
ES6881-50UL
100UL
£ POA
ES6881-100UL
About this Product
SKU:
ES6881
Additional Names:
PTCH1; PTCH; Protein patched homolog 1; PTC; PTC1
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog; a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis; as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome; esophageal squamous cell carcinoma; trichoepitheliomas; transitional cell carcinomas of the bladder; as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described; but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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