PAF-R rabbit pAb
Product Sizes
50UL
£ POA
ES6880-50UL
100UL
£ POA
ES6880-100UL
About this Product
- SKU:
- ES6880
- Additional Names:
- PTAFR; PAFR; Platelet-activating factor receptor; PAF-R; PAFr
- Application:
- Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation; tumor growth; angiogenesis; metastasis; and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C; D; A2; mitogen-activated protein kinases (MAPKs); and the phosphatidylinositol-calcium second messenger system. Following PAFR activation; cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation; internalization; and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Aug 2011];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human PTAFR. AA range:194-243
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
