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Antibodies

ERK 2 rabbit pAb

Product Sizes
50UL
£ POA
ES6814-50UL
100UL
£ POA
ES6814-100UL
About this Product
SKU:
ES6814
Additional Names:
MAPK1; ERK2; PRKM1; PRKM2; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the MAP kinase family. MAP kinases; also known as extracellular signal-regulated kinases (ERKs); act as an integration point for multiple biochemical signals; and are involved in a wide variety of cellular processes such as proliferation; differentiation; transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation; this kinase translocates to the nucleus of the stimulated cells; where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein; but differing in the UTRs; have been reporte
Immunogen:
The antiserum was produced against synthesized peptide derived from human p42 MAPK. AA range:136-185
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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