PKAα cat (phospho Ser338) rabbit pAb
Product Sizes
50UL
£ POA
ES6739-50UL
100UL
£ POA
ES6739-100UL
About this Product
- SKU:
- ES6739
- Additional Names:
- PRKACA; PKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes one of the catalytic subunits of protein kinase A; which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits; in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes; including differentiation; proliferation; and apoptosis. Constitutive activation of this gene caused either by somatic mutations; or genomic duplications of regions that include this gene; have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern
- Immunogen:
- Synthesized phospho-peptide around the phosphorylation site of human PKAα cat (phospho Ser338)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
