N-Shc rabbit pAb
Product Sizes
50UL
£ POA
ES6607-50UL
100UL
£ POA
ES6607-100UL
About this Product
- SKU:
- ES6607
- Additional Names:
- SHC3; NSHC; SHCC; SHC-transforming protein 3; Neuronal Shc; N-Shc; Protein Rai; SHC-transforming protein C; Src homology 2 domain-containing-transforming protein C3; SH2 domain protein C3
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.;PTM:Tyrosine phosphorylated.;similarity:Contains 1 PID domain.;similarity:Contains 1 SH2 domain.;subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner. Once activated; binds to GRB2. Interacts with activated EGF receptors.;tissue specificity:Mainly expressed in brain. Hardly detectable in other tissues; except in pancreas. Highly expressed in the cerebral cortex; frontal and temporal lobes; occipital pole; hippocampus; caudate nucleus and amygdala. Expressed at low level in the cerebellum; medulla and spinal cord.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SHC3. AA range:291-340
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
