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Antibodies

MYLK rabbit pAb

Product Sizes
50UL
£ POA
ES6317-50UL
100UL
£ POA
ES6317-100UL
About this Product
SKU:
ES6317
Additional Names:
MYLK; MLCK; MLCK1; MYLK1; Myosin light chain kinase; smooth muscle; MLCK; smMLCK; Kinase-related protein; KRP; Telokin
Application:
Western Blot, ELISA, Immunohistochemistry
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
myosin light chain kinase(MYLK) Homo sapiens This gene; a muscle member of the immunoglobulin gene superfamily; encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition; using a separate promoter in an intron in the 3' region; it encodes telokin; a small protein identical in sequence to the C-terminus of myosin light chain kinase; that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been
Immunogen:
The antiserum was produced against synthesized peptide derived from human MYLK. AA range:1701-1750
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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