MLK1/2 (phospho Thr312/266) rabbit pAb
Product Sizes
50UL
£ POA
ES6249-50UL
100UL
£ POA
ES6249-100UL
About this Product
- SKU:
- ES6249
- Additional Names:
- MAP3K9; MLK1; PRKE1; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K10; MLK2; MST; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.;cofactor:Magnesium.;enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.;function:Activates the JUN N-terminal pathway.;PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.;similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.;similarity:Contains 1 protein kinase domain.;similarity:Contains 1 SH3 domain.;subunit:Homodimer.;tissue specificity:Expressed in epithelial tumor cell lines of colonic; breast and esophageal origin.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MLK1/2 around the phosphorylation site of Thr312/266. AA range:281-330
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
